Software Engineer

Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity

Praxis Precision Medicines is building a strong pipeline of Software Engineering talent to support the continued evolution of our eDiary and clinical data platforms. Engineers in this role will first contribute to and grow within our eDiary ecosystem—a regulated, patient-facing platform used across our Epilepsy portfolio. Our engineers work across modern web and mobile applications, secure clinical data platforms, cloud infrastructure, distributed system architectures, API design, auditability frameworks, identity and access control systems, and production observability. When you apply to this position, your profile will be considered for current and future Software Engineer openings supporting the eDiary platform and adjacent clinical systems.

Primary Responsibilities

• Design, develop, and maintain reliable, production-grade code across frontend, backend, and data layers, implementing software solutions that meet clinical, operational, and regulatory requirements
• Deploy and operate services in a cloud environment (AWS preferred) and contribute to architecture and design reviews with a focus on reliability, scalability, and security
• Debug and resolve production issues across distributed and asynchronous workflows; diagnose performance bottlenecks; and own incident response, including root cause analysis and durable fixes that prevent recurrence
• Collaborate with QA, Clinical Operations, Clinical Development, Product, and IT stakeholders to translate requirements into validated releases
• Design APIs and data models that preserve audit trails, version history, and system traceability; and improve system observability through structured logging, monitoring, and alerting
• Uphold high standards for data integrity, security, and regulatory compliance across all systems

Qualifications and Key Success Factors

• Bachelor’s degree in Software Engineering or equivalent practical experience
• 3+ years of non-internship professional software development experience, with demonstrated ability to design, build, and operate production software systems end-to-end
• Demonstrated experience using AI-assisted development tools (e.g., code generation, automated testing, debugging copilots) to improve engineering productivity and code quality, with ability to critically evaluate AI-generated outputs for correctness, security, and maintainability
• Strong foundation in software engineering fundamentals: data structures and algorithms, API and interface design, relational data modeling and transactional integrity, and separation of concerns
• Demonstrated ability to debug complex issues across multiple layers (client, API, database, infrastructure) and trace issues in distributed or asynchronous systems using logs, metrics, and instrumentation
• Experience deploying and operating applications in a cloud environment (any major provider), including networking, access control, configuration, and monitoring; and experience designing secure systems including authentication and authorization flows
• Experience implementing production-grade monitoring, alerting, and CI/CD practices; and ability to work effectively in a remote-first, high-accountability environment
• The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You’ll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Annualized Base Salary

$105,000 — $125,000 USD

Compensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive.  This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future?  We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP.  We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.  Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring.  We aim high, collaborate hard, and produce results.  Let’s achieve the impossible together!

Company Overview

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust , Ownership , Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion

Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE ® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

Attention: Job Scam Alert

Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com .

Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.